A destination not commonly on the map for most travelers is Greensboro, North Carolina. Situated in the upper portion of "The Triad" (Winston-Salem, High Point and Greensboro), Greensboro has access to many alternative forms of transportation. Whether you are traveling by Amtrak, Greyhound, Part Buses (serving a large portion of upper North Carolina), or Carolina Trail-ways, Greensboro is worth the stop.
The most active calendar day for the city is the first friday of every month. Appropriately named, "First Friday" of "Downtown Fridays" is a popular event. Many of the art galleries and vendors change their display for the event. Often times tent vendors will be available selling local arts and crafts at the Indie Market. A walking tour guide is available from downtownfridays.com.
I recommend visiting on these dates as they will be the most interactive and cultural days for the city. The City park is filled with live music, and the businesses sometimes serve free food and drinks or give away prizes.
Apart from monthly events, Greensboro is also known for its beautiful parks and museums. The International Civil Rights Center and Museum recently opened downtown at the location of the famous sit-ins of February 1st, 1960. The Guilford Courthouse National Military park on Battleground Ave is also rich in history as it was an actual battleground during the American Revolutionary War.
Also, if you are interested in using the recently update public transit system, feel free to look up times and locations from the Greensboro Transit Authority website. As a tip, however, Saturday and Sunday times are not very flexible. It is best to plan accordingly.