If you find yourself in downtown Knoxville for the night, skip the Radisson, Hilton, or Hyatt, and check the Hotel St. Oliver for vacancies. It has a great small city B&B feel (except without the breakfast), and offers a variety of rooms at different prices.
This small, lovely hotel (only about 20 rooms, I think) is in a historic building right off Market Square. Each renovated room has been tastefully decorated with restored antique furniture and other special touches. (This is where actor Patricia Neal has her favorite room reserved when she's in town.)
Downstairs, off the lobby, there's also a small but decadent library/parlor to entertain or play a quiet game of backgammon in.
We were amazed at the personal service we received when we booked almost the entire hotel for our wedding party, families, and friends.
Nancy Oslin (manager) was incredibly patient with changing reservations, late comings and goings, and special requests. All of our guests were very pleased. (We were also quite pleased with our honeymoon suite.)