A nice hotel very conveniently located near the Expo Guadalajara site. If you are an old visitor to Guadalajara, you may remember it as the Hyatt.
The gym is named the Olympus Club and is nicely equipped with modern machines. Go and enjoy a nice swim at the heated outdoor pool and then get inside to spend some time at the Jacuzzi or the the steam bath, both in good condition, so much that a lot of locals come to enjoy the Olympus Club on a daily basis.
The restaurant has a very good variety and the prices are right, but you can also eat at the Italian specialty one, where they make an impressive fettuccine.
In front of the hotel there is a large mall, Plaza del Sol, just across an avenue. An underground plaza with megaplex cinemas is just 2 blocks south, the Expo Guadalajara is within a 15-minute walk or a very short taxi ride, several good restaurants are within 10-minute taxi rides, and there are several nightclubs. If you are doing business here, you don't need to go downtown at all.
Their website is http://www.ichotelsgroup.com/h/d/icon/hd/gdlha.