The first thing you should know is that the beds at the Siena are among the most comfortable on earth. They are comparable with those at the Ritz-Carlton in San Francisco. They are awesome. They are the reason I bring my Princess and the Pea butt there time and again.
Rooms are attractively furnished, with high thread-count Egyptian cotton sheets, down comforters, and comfortable/stylish furniture. Business amenities include high-speed Internet access (though you might do well to bring your own ethernet cable, as they were short on one visit), web TV, safes, and two-line speaker phones.
We upgraded for a pittance to a one-bedroom suite, and it was fabulous. It featured a marble bathroom with a long and deep jacuzzi tub, separate glass stall shower, and large, plush bath towels. There were also large screen TVs in both rooms, a small kitchen area with sink, refrigerator, and coffee maker, a dining table for four, and a very comfortable sofa and chairs.
The fourth floor of the hotel has a swimming pool, gym, and spa on it--all very good-quality facilities.
Staff are pleasant, helpful, and seem genuinely proud of their place; it is the nicest hotel in Reno.
Dining options are good, though we didn't choose to eat there (yet). See my restaurant picks, and you'll see why.
Best of all are the prices. There are very often great specials (rooms for $50/night, upgrades to a suite for not much more, etc.).
Siena website