Stayed in the Semiramis for 2 nights in late November. We were lucky enough to get a Nile view room with club lounge access. The room was pretty much as you would expect from an IC hotel but with a reasonable size balcony and slightly worse plumbing. The club lounge was great, a very good range of breakfast and evening snacks were on offer - these included Egyptian standards which was nice.
The hotel is very, very secure and the area of the city that it is located in is heavily policed, able to happily stroll from the hotel to the Egyptian museum and the metro. There is a nice gym and pool. The service is great from all hotel staff.
Would definitely stay in this hotel again.