Early February - the Chocolate Festival, a unique opportunity for trying whole meals based on chocolate, and take advantage of the free samples offered by chocolate factories.
All through the summer - Umbria Jazz, international stars performing live in theatres, smaller venues, and on the streets; from Dixieland to avant-garde, the whole spectrum is represented.
All through the year - the National Gallery holds one of the finest collections of Renaissance paintings in the world. All around town, "minor" hot spots of antiquarian interest - from Etruscan to Late Renaissance - are easily accessible.
Quick Tips:
Most museums and art exhibits will provide multiple tickets, allowing access to a number (normally three) of different venues for a reduced fare. Usually, the venues included are to be visited on the same day.
The National Gallery tends to be crowded due to its renowned status. But it closes at 7:30pm, and especially in the off-season, a satisfactory tour of the premises can be done by getting in at 6pm, when most visitors would be getting out.
Best Way To Get Around:
The best way to get around Perugia is on foot.
No bicycles - there's too many steep climbs and stairways.
No cars - this town was built when the donkey was the top of the line in luxury transportation.
Public transportation, in the form of huge nafta-powered buses, can be confusing and does not run at night.