This club makes the claim that it is the "biggest club in Middle Europe." My friends and I referred to it as "The Five Story" club. Each floor is dedicated to a different type of music, with the top floor set up as a lounge rather than a dance club. Whether you like hip-hop, ‘80s, or electronica, Karlovy Lazne is the place to check out. It is also in an extremely scenic location right on the river. I was there just after the major floods of 2002, so the riverfront was slightly depressed, but I can envision it being a very nice place to hang around outside.
The one thing I will say, though, is that Karlovy Lazne is quite touristy. It seems as though everyone and their mom visits this club if they're in Prague. It is the most visible and biggest club in Prague. Oh yeah, it is also really funny to see Euro's dressed up in "hip-hop" clothing. I saw more kids in full NBA uniforms with headbands and the like than I've seen anywhere else.
Lastly, the last time I was at the club, I remember women in skin-tight red outfits handing out free cigarettes. This is Europe, but still it was a shocker to me. I'm from California, where smoking isn’t allowed anywhere!