When, if like me, you get tired of attempting to speak pidgin Czech and having your efforts awarded with a confused look . . . then Molly Malones is a welcome relief. An Irish pub run by mostly Irish staff, your inability to speak Czech will pass by unnoticed here. Serves Guiness, cider, as well as the usual lager, wines, and spirits. It's a little more expensive than elsewhere, but it does a magnificent Irish breakfast, there's good pub food the rest of the day, a roaring fire, and great Irish music.
Note that, although the Oct 2002 edition of Rough Guide to Prague has this pub's address right, it is shown in the wrong place on their map . . . The place can be found off Dlouha Kozi towards Anezsky Klaster.