Acme is a New Orleans institution. You can tell this by the lines outside everynight. The interior is pretty basic, so if you're looking for ambience, you have been warned.
We always make a point of eating here whenever we're in New Orleans. The prices can't be beat for Cajun food. The oysters and crawfish are a good deal. Fried food is the other big draw on the menu. The poboys are a big and yummy. My only complaint is the gumbo -- it tastes kinda "swampy" to me. If fried food is not your thing (that's me), the sampler plate is a good pick.